The challenge of internalizing impermeable molecules into cells persists in drug development, particularly concerning water-soluble bioactive compounds that cannot diffuse across the cell membrane. To overcome this problem, various artificial transporters, including polymers, lipids, and cationic penetrating peptides, have been engineered. The challenge of internalizing impermeable molecules into cells persists in drug development, particularly concerning water-soluble bioactive compounds that cannot diffuse across the cell membrane. To overcome this problem, various artificial transporters, including polymers, lipids, and cationic penetrating peptides, have been engineered. Biochemistry Analytical Chemistry Phys.org – latest science and technology news stories
First set of rational design principles for chaotropic membrane transporters
