Certain foods and drinks, such as grape juice, broccoli, spinach, cheese, red wine, and coffee, can interact with various medications leading to reduced effectiveness or severe side effects. These interactions can affect drug metabolism, blood pressure, blood clotting, and central nervous system stimulation. Certain foods and drinks, such as grape juice, broccoli, spinach, cheese, red wine, and coffee, can interact with various medications leading to reduced effectiveness or severe side effects. These interactions can affect drug metabolism, blood pressure, blood clotting, and central nervous system stimulation. Health and Fitness, Health Tips, Exercises & Workout Tips, Diet & Wellness | Times of India Lifestyle