vrinda sharma

Simplified redesign of proteins can improve ligand binding

Simplified redesign of proteins can improve ligand binding

In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, including cell signaling and enzymatic action. In biotechnology and medicine, the ability of researchers to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient…

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Seeing the unseen: New method reveals ‘hyperaccessible’ window in freshly replicated DNA

Seeing the unseen: New method reveals ‘hyperaccessible’ window in freshly replicated DNA

DNA replication is happening continuously throughout the body, as many as trillions of times per day. Whenever a cell divides—whether to repair damaged tissue, replace old cells, or simply to help the body grow—DNA is copied to ensure the new cells carry the same genetic instructions. DNA replication is happening continuously throughout the body, as many…

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Peptides that can remove microplastics identified

Peptides that can remove microplastics identified

Researchers have identified peptides that can help remove microplastics from the environment by combining biophysical modeling, molecular dynamics, quantum computing, and reinforcement learning. The ultimate goal of the work is peptide-based technologies that can find, capture, and destroy microscopically tiny plastic particles. The work is published in PNAS Nexus. Researchers have identified peptides that can help…

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Building sentence structure may be language-specific, brain activity study finds

Building sentence structure may be language-specific, brain activity study finds

Do speakers of different languages build sentence structure in the same way? In a neuroimaging study published in PLOS Biology, scientists from the Max Planck institute for Psycholinguistics, Donders Institute and Radboud University in Nijmegen recorded the brain activity of participants listening to Dutch stories. In contrast to English, sentence processing in Dutch was based…

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Illuminating an asymmetric gap in a topological antiferromagnet

Illuminating an asymmetric gap in a topological antiferromagnet

Topological insulators (TIs) are among the hottest topics in condensed matter physics today. They’re a bit strange: Their surfaces conduct electricity, yet their interiors do not, instead acting as insulators. Physicists consider TIs the materials of the future because they host fascinating new quantum phases of matter and have promising technological applications in electronics and…

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Trump Announces $100 Billion Stargate A.I. Initiative With OpenAI, Oracle and SoftBank

OpenAI, Oracle and SoftBank formed a new joint venture called Stargate to invest in data centers, building on major U.S. investments in the technology. Artificial Intelligence, Computers and the Internet, Data Centers, OpenAI Labs, Oracle Corporation, SOFTBANK Corporation, Trump, Donald J OpenAI, Oracle and SoftBank formed a new joint venture called Stargate to invest in data centers,…

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