Before the hippocampus goes down memory lane, it takes a detour Before the hippocampus goes down memory lane, it takes a detour  Science

Enhanced antibacterial skin inflammation is an adaptation of the itch-scratch cycle Enhanced antibacterial skin inflammation is an adaptation of the itch-scratch cycle  Science

To many in the scientific community, the 1975 Asilomar Conference on Recombinant DNA stands as a singular achievement. This experiment in governance seemed to demonstrate that citizens could trust scientists to anticipate their fields’ risks and propose … To many in the scientific community, the 1975 Asilomar Conference on Recombinant DNA stands as a singular achievement….

The latest in science and policy The latest in science and policy  Science

After many years of partisan politics, increasingly divisive language, finger-pointing and inflammatory speech have contributed to an environment of fear and uncertainty, affecting not just political dynamics but also the priorities and perceptions of young people. After many years of partisan politics, increasingly divisive language, finger-pointing and inflammatory speech have contributed to an environment of fear…

Studying the functional consequences of structural variants (SVs) in mammalian genomes is challenging because (i) SVs arise much less commonly than single-nucleotide variants or small indels and (ii) methods to generate, map, and characterize SVs in … Studying the functional consequences of structural variants (SVs) in mammalian genomes is challenging because (i) SVs arise much less…

Highly concentrated solutions of asymmetric semiconductor magic-sized clusters (MSCs) of cadmium sulfide, cadmium selenide, and cadmium telluride were directed through a controlled drying meniscus front, resulting in the formation of chiral MSC … Highly concentrated solutions of asymmetric semiconductor magic-sized clusters (MSCs) of cadmium sulfide, cadmium selenide, and cadmium telluride were directed through a controlled drying…

Social animals live in groups and interact volitionally in complex ways. However, little is known about neural responses under such natural conditions. Here, we investigated hippocampal CA1 neurons in a mixed-sex group of five to 10 freely behaving wild … Social animals live in groups and interact volitionally in complex ways. However, little is known about…

Itch is a dominant symptom in dermatitis, and scratching promotes cutaneous inflammation, thereby worsening disease. However, the mechanisms through which scratching exacerbates inflammation and whether scratching provides benefit to the host are largely … Itch is a dominant symptom in dermatitis, and scratching promotes cutaneous inflammation, thereby worsening disease. However, the mechanisms through which scratching exacerbates…

We lack tools to edit DNA sequences at scales necessary to study 99% of the human genome that is noncoding. To address this gap, we applied CRISPR prime editing to insert recombination handles into repetitive sequences, up to 1697 per cell line, which … We lack tools to edit DNA sequences at scales necessary to study…