Autoregulated splicing of TRA2β programs T cell fate in response to antigen-receptor stimulation | Science

Autoregulated splicing of TRA2β programs T cell fate in response to antigen-receptor stimulation | Science

T cell receptor (TCR) sensitivity to peptide–major histocompatibility complex (MHC) dictates T cell fate. Canonical models of TCR sensitivity cannot be fully explained by transcriptional regulation. In this work, we identify a posttranscriptional … T cell receptor (TCR) sensitivity to peptide–major histocompatibility complex (MHC) dictates T cell fate. Canonical models of TCR sensitivity cannot be fully explained by transcriptional regulation. In this work, we identify a posttranscriptional …  Science

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