Biomolecular condensate ‘molecular putty’ properties found encoded in protein sequence

Biomolecular condensates are membraneless hubs of condensed proteins and nucleic acids within cells, which researchers are realizing are tied to an increasing number of cellular processes and diseases. Studies of biomolecular condensate formation have uncovered layers of complexity, including their ability to behave like a viscoelastic material. However, the molecular basis for this putty-like property was unknown. Biomolecular condensates are membraneless hubs of condensed proteins and nucleic acids within cells, which researchers are realizing are tied to an increasing number of cellular processes and diseases. Studies of biomolecular condensate formation have uncovered layers of complexity, including their ability to behave like a viscoelastic material. However, the molecular basis for this putty-like property was unknown. Molecular & Computational biology Phys.org – latest science and technology news stories

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