Tornado leaves five dead in Iowa

A tornado that ripped through the midwestern US state of Iowa killed five people and left dozens injured, officials said, with homes smashed to pieces and cars thrown through the air. A tornado that ripped through the midwestern US state of Iowa killed five people and left dozens injured, officials said, with homes smashed to pieces…

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Birth of universe’s earliest galaxies observed for first time

Using the James Webb Space Telescope, University of Copenhagen researchers have become the first to see the formation of three of the earliest galaxies in the universe, more than 13 billion years ago. The sensational discovery contributes important knowledge about the universe and is now published in Science. Using the James Webb Space Telescope, University of…

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Uncertainty clouds UN talks on biopiracy treaty

UN talks to create a global treaty to combat biopiracy and the exploitation of genetic resources hung in the balance Thursday, a day before an agreement was due to be signed. UN talks to create a global treaty to combat biopiracy and the exploitation of genetic resources hung in the balance Thursday, a day before an…

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Molecular cascades and cell type–specific signatures in ASD revealed by single-cell genomics | Science

Genomic profiling in postmortem brain from autistic individuals has consistently revealed convergent molecular changes. What drives these changes and how they relate to genetic susceptibility in this complex condition are not well understood. We … Genomic profiling in postmortem brain from autistic individuals has consistently revealed convergent molecular changes. What drives these changes and how they…

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Single-cell genomics and regulatory networks for 388 human brains | Science

Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet little is understood about how genetic variants influence cell-level gene expression. Addressing this, we uniformly processed single-nuclei, multiomics … Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet little is understood about how genetic variants…

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Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood | Science

The molecular pathology of stress-related disorders remains elusive. Our brain multiregion, multiomic study of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) included the central nucleus of the amygdala, hippocampal dentate … The molecular pathology of stress-related disorders remains elusive. Our brain multiregion, multiomic study of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD)…

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