Chemically induced proximity reveals a Piezo-dependent meiotic checkpoint at the oocyte nuclear envelope | Science

Chemically induced proximity reveals a Piezo-dependent meiotic checkpoint at the oocyte nuclear envelope | Science

Sexual reproduction relies on robust quality control during meiosis. Assembly of the synaptonemal complex between homologous chromosomes (synapsis) regulates meiotic recombination and is crucial for accurate chromosome segregation in most eukaryotes. … Sexual reproduction relies on robust quality control during meiosis. Assembly of the synaptonemal complex between homologous chromosomes (synapsis) regulates meiotic recombination and is crucial for accurate chromosome segregation in most eukaryotes. …  Science

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