Chromatin plasticity predetermines neuronal eligibility for memory trace formation | Science

Chromatin plasticity predetermines neuronal eligibility for memory trace formation | Science

Memories are encoded by sparse populations of neurons but how such sparsity arises remains largely unknown. We found that a neuron’s eligibility to be recruited into the memory trace depends on its epigenetic state prior to encoding. Principal neurons in … Memories are encoded by sparse populations of neurons but how such sparsity arises remains largely unknown. We found that a neuron’s eligibility to be recruited into the memory trace depends on its epigenetic state prior to encoding. Principal neurons in …  Science

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