Human genetics provides clues to why DNA regulatory regions get ‘loopy’

Human genetics provides clues to why DNA regulatory regions get ‘loopy’

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted upon by an enzyme called RNA polymerase. This is a molecular machine which can read DNA and create a matching strand of RNA which is then used to make proteins. RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted upon by an enzyme called RNA polymerase. This is a molecular machine which can read DNA and create a matching strand of RNA which is then used to make proteins. RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Molecular & Computational biology Phys.org – latest science and technology news stories

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