Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae | Science

Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae | Science

Peroxisomes are vital but often overlooked metabolic organelles. We found that excessive interferon signaling remodeled macrophage peroxisomes. This loss of peroxisomes impaired inflammation resolution and lung repair during severe respiratory viral … Peroxisomes are vital but often overlooked metabolic organelles. We found that excessive interferon signaling remodeled macrophage peroxisomes. This loss of peroxisomes impaired inflammation resolution and lung repair during severe respiratory viral …  Science

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