New agent inhibits Staphylococcus aureus toxin—giving hope to pneumonia patients

New agent inhibits Staphylococcus aureus toxin—giving hope to pneumonia patients

An international research group led by the Helmholtz Center for Infection Research (HZI) has discovered a promising new drug candidate against severe lung infections caused by the hospital germ Staphylococcus aureus. The study, which has just been published in Cell Host & Microbe, describes for the first time how small molecules from the quinoxalinedione class specifically block the bacterial toxin α-hemolysin—a key trigger of tissue damage and inflammation. An international research group led by the Helmholtz Center for Infection Research (HZI) has discovered a promising new drug candidate against severe lung infections caused by the hospital germ Staphylococcus aureus. The study, which has just been published in Cell Host & Microbe, describes for the first time how small molecules from the quinoxalinedione class specifically block the bacterial toxin α-hemolysin—a key trigger of tissue damage and inflammation. Cell & Microbiology Molecular & Computational biology Phys.org – latest science and technology news stories

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