In order to reach their target, for instance a tumor, immune cells have to leave the bloodstream or lymphatic vessels and migrate through connective tissue. Until now, scientists presumed that immune cells migrated through tissue by constantly changing their shape and therefore squeezing through the smallest pores and openings. In order to reach their target, for instance a tumor, immune cells have to leave the bloodstream or lymphatic vessels and migrate through connective tissue. Until now, scientists presumed that immune cells migrated through tissue by constantly changing their shape and therefore squeezing through the smallest pores and openings. Molecular & Computational biology Phys.org – latest science and technology news stories