Novel strategy proposed for selectively targeting G-quadruplex at specific genome loci

Novel strategy proposed for selectively targeting G-quadruplex at specific genome loci

DNA G-quadruplexes (G4s) are a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Although DNA G4s are thought to be involved in various biological processes, in many cases their causative effects are largely unclear due to lack of suitable strategies for selectively stabilizing DNA G4 at specific loci. DNA G-quadruplexes (G4s) are a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Although DNA G4s are thought to be involved in various biological processes, in many cases their causative effects are largely unclear due to lack of suitable strategies for selectively stabilizing DNA G4 at specific loci. Cell & Microbiology Molecular & Computational biology Phys.org – latest science and technology news stories

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