Researchers uncover why cells struggle to fully change identity in reprogramming efforts

A new study has shed light on the challenges of converting one type of specialized cell into another, a process critical for advances in regenerative medicine. Despite recent progress in the field, a key obstacle in maintaining the new identity of reprogrammed cells lies in their original DNA methylation patterns—crucial markers that define cell identity. A new study has shed light on the challenges of converting one type of specialized cell into another, a process critical for advances in regenerative medicine. Despite recent progress in the field, a key obstacle in maintaining the new identity of reprogrammed cells lies in their original DNA methylation patterns—crucial markers that define cell identity. Cell & Microbiology Molecular & Computational biology Phys.org – latest science and technology news stories