Scientists have prototyped a new method for “rationally engineering” enzymes to deliver improved performance. They have devised an algorithm, which takes into account an enzyme’s evolutionary history, to flag where mutations could be introduced with a high likelihood of delivering functional improvements. Scientists have prototyped a new method for “rationally engineering” enzymes to deliver improved performance. They have devised an algorithm, which takes into account an enzyme’s evolutionary history, to flag where mutations could be introduced with a high likelihood of delivering functional improvements. Biotechnology Molecular & Computational biology Phys.org – latest science and technology news stories