Visualization of the first contact between the earliest reported human coronavirus and its human receptor molecule

Visualization of the first contact between the earliest reported human coronavirus and its human receptor molecule

Coronavirus 229E is the earliest reported human coronavirus (hCoV-229E). Researchers used cryo-EM, glycoproteomics, and modeling to generate the atomic structure of a fully glycosylated and membrane-bound hCoV-229E spike protein bound to its host receptor, human aminopeptidase N (hAPN). Coronavirus 229E is the earliest reported human coronavirus (hCoV-229E). Researchers used cryo-EM, glycoproteomics, and modeling to generate the atomic structure of a fully glycosylated and membrane-bound hCoV-229E spike protein bound to its host receptor, human aminopeptidase N (hAPN). Cell & Microbiology Molecular & Computational biology Phys.org – latest science and technology news stories

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